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, Biology, Universidad de los Andes, Colombia 1997.

Inducible knockdown of VPS41 resulted in dramatic vacuole fragmentation phenotypes and demonstrated a critical role for HOPS in vacuole fusion.

, Proceedings of the National Academy of Sciences of the United States of America 2017• PB 780 Plant Molecular Biology Fall Publications• While many plant cells contain one large vacuole, Marcela Rojas-Pierce wants to examine how, in some model plant Arabidopsis cells, vacuoles control the opening and closing of stomata - plant "pores" that must be regulated to balance carbon dioxide intake and the release of oxygen via water vapor.

She added that this system is similar in other eukaryotes, or organisms with a cell nucleus.

, Proceedings of the National Academy of Sciences 2018• Believed to be a kind of plant garbage dump, with multiple roles in storage and recycling, vacuoles are also critical for pollen development, with sterility the consequence if the process goes awry.

Note to editors: An abstract of the paper follows.

"But this beautiful and elaborate system must be tightly regulated to properly ensure the plant's response to the environment.

, Journal of Experimental Botany 2016• The study was supported by the National Aeronautics and Space Administration under grant NNX13AM49G and the National Science Foundation under grants DBI-1624613 and MCB-1244354 Paper co-authors included Carla Brillada, Jiameng Zheng and Eliezer Rovira-Diaz from NC State, and Falco Kruger, Jana Christin Askani and Karin Schumacher from Heidelberg University.

HOPS function is not well characterized in plants, but roles in embryogenesis and pollen tube elongation have been reported.